Regulation of inflammation by adipocytes through interaction with macrophages and in atypical antipsychotic drug treatments
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P-88: Mast Cells Number and Distribution and Myoid Cells Population Are Impressed by Sulpiride Antipsychotic Drug
Background: Spermatogenesis is under the control of variety of factors, which include mast cells. Any changes in testicular mast cells’ number and distribution resulting in deterioration of comlex regulation and fine-turning of spermatogenesis. Increased number of mast cells and their abnormal spread pattern have been described in the testis with fertility disturbances. Mast cells’ tryptase enz...
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Background: Prescription of the atypical antipsychotic drugs like as Sulpiride for the treatment of schizophrenic patients was increased because of their less side effects. This study was aimed to evaluate the effect of sulpiride on hormonal milieu of adult male mice namely their serum level of prolactin and sexual hormones. Materials and Methods: 24 adult male mice were divided in three groups...
متن کاملP-4: Effect of Reduced FSH Serum Concentration Induced by Sulpiride Atypical Antipsychotic Drug on Repopulation Index and Number of Primery Spermatocyte Cells in Adult Male Mice
Background: Usage of some atipycal antipsychotic drugs like sulpiride has severed effects on male fertility by impressions on sexual hormones secretion. These hormones regulate male germ cells proliferation and differentiation. In the present study we sought to elucidate the impact of sulpiride on serum prolactin and FSH concentration. Also effect of FSH on spermatogonium A/B (repopulation inde...
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Background and Purpose: In recent years, review of opioid system and its changes in the psychopathology of schizophrenia through thear probable role our on neuronal synopses and cell body of dopaminergic neurons and also decrease dopamine secretion from acumbans nuclei and effects of opium agonists in treatment of those patients has been adventajes for clinicians. Materials and methods: I...
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Obesity-induced adipose inflammation is characterized by recruitment of macrophages to adipose tissue and release of inflammatory cytokines. 4-1BB, a costimulatory receptor, modulates inflammatory processes through interaction with its ligand 4-1BBL on immune cell surfaces. In this study, we examined whether a 4-1BB/4-1BBL interaction between adipocytes and macrophages participates in obesity-i...
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تاریخ انتشار 2015